Induction of Neurolathyrism in Guinea Pig Fed with Lathyrus sativus Diet

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Lessons from neurolathyrism: A disease of the past & the future of Lathyrus sativus (Khesari dal)

Neurolathyrism is past history in India since Lathyrus sativus (khesari dal) is no longer used as a staple. A consensus has evolved that khesari dal is harmless as part of a normal diet. L-ODAP (β-N-oxalyl-l-α-diamino propionic acid) the neurotoxic amino acid, from this pulse, is detoxified in humans but not in animals but still no laboratory animal is susceptible to it under acceptable feeding...

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contents of Lathyrus (Lathyrus cicera) as an ingredient in pig

20 Lathyrus cicera is a grain legume that is well adapted to grow in low rainfall regions. 21 However, it contains a neurotoxin, 3-(-N-oxylyl)-L-2,3-diaminopropionic acid (ODAP), 22 which can cause paralysis of the lower limbs, known as “lathyrism”. An experiment was 23 conducted to measure the nutrient content and ileal digestible amino acid content of a recently 24 released low ODAP lathyrus ...

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ژورنال

عنوان ژورنال: Current Developments in Nutrition

سال: 2020

ISSN: 2475-2991

DOI: 10.1093/cdn/nzaa057_039